Status:
COMPLETED
Efficacy and Mechanisms of Virtual Reality Treatment of Phantom Leg Pain
Lead Sponsor:
Albert Einstein Healthcare Network
Collaborating Sponsors:
University of Pennsylvania
University of Washington
Conditions:
Phantom Limb Pain
Eligibility:
All Genders
18-100 years
Phase:
NA
Brief Summary
After amputation of an arm or leg, up to 90% of subjects experience a "phantom limb", a phenomenon characterized by persistent feelings of the missing limb. Many subjects with a phantom limb experienc...
Detailed Description
Almost 2 million people in the US have had an amputation and up to 90% of people with limb amputation experience the persistent sensation of the missing extremity, a phenomenon known as a "phantom lim...
Eligibility Criteria
Inclusion
- Age 18 - 100 years
- Capacity to provide Informed Consent
- Unilateral above or below knee amputation more than 3 months prior to enrollment
- Absence of cognitive impairment, operationally defined as a Montreal Cognitive Assessment score of 18 or greater
- Pain averaged over the preceding 1 month in the phantom limb rated as greater than 4 on a scale of 0-10.
Exclusion
- History of significant medical or neurological disorder such as stroke or moderate to severe traumatic brain injury (operationally defined as loss of consciousness for more than 30 minutes)
- History of significant or poorly controlled psychiatric disorders
- Current significant depression or anxiety as judged by the Hospital Anxiety and Depression Scale (HADS) (Zigmond \& Snaith, 1983).
- Current abuse of alcohol or drugs, prescription or otherwise
- Nursing a child, pregnant, or intent to become pregnant during the study
Key Trial Info
Start Date :
May 10 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 6 2025
Estimated Enrollment :
46 Patients enrolled
Trial Details
Trial ID
NCT05296265
Start Date
May 10 2022
End Date
April 6 2025
Last Update
October 3 2025
Active Locations (3)
Enter a location and click search to find clinical trials sorted by distance.
1
Moss Rehabilitation Research Institute
Elkins Park, Pennsylvania, United States, 19027
2
University of Pennsylvania
Philadelphia, Pennsylvania, United States, 19104
3
University of Washington-Harborview Medical Center
Seattle, Washington, United States, 98104