Status:
COMPLETED
Adipose-derived Stem Cell Conditioned Media as a Novel Approach for Hair Regrowth in Male Androgenetic Alopecia
Lead Sponsor:
Dr. dr. Lili Legiawati, SpKK(K)
Collaborating Sponsors:
Kementerian Riset dan Teknologi / Badan Riset dan Inovasi Nasional, Indonesia
PT. Kimia Farma (Persero) Tbk
Conditions:
Alopecia, Androgenetic
Hair Loss/Baldness
Eligibility:
MALE
25-58 years
Phase:
PHASE3
Brief Summary
This study investigated the efficacy of adipose derived stem cell conditioned media (ADSC-CM) combined with minoxidil for hair regeneration therapy in male AGA.
Detailed Description
This study was a double-blind, randomized clinical trial (RCT). Two concentrations of ADSC-CM were utilized: concentrated and non-concentrated ADSC-CM. The scalp was divided vertically in half; one si...
Eligibility Criteria
Inclusion
- males aged 25-58 years old
- Hamilton-Norwood criteria grades II to VI
- cessation of anti-androgens and minoxidil treatment for at least one month
Exclusion
- patients with hair loss other than AGA, such as alopecia areata, chemotherapy-induced alopecia, autoimmune-induced alopecia, and scalp malignancies;
- patients receiving 5-alpha reductase inhibitor therapy;
- patients who had received growth factor treatment (platelet-rich plasma or microneedling) for at least six months prior to the study; and
- history of hypertrophic scars or blood clotting disorders.
Key Trial Info
Start Date :
October 11 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 3 2021
Estimated Enrollment :
37 Patients enrolled
Trial Details
Trial ID
NCT05296863
Start Date
October 11 2021
End Date
December 3 2021
Last Update
March 25 2022
Active Locations (1)
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1
Universitas Indonesia
Jakarta Pusat, Jakarta Special Capital Region, Indonesia, 10430