Status:
RECRUITING
The Effect of Bethanechol on Tracheobronchomalacia
Lead Sponsor:
Arkansas Children's Hospital Research Institute
Conditions:
Tracheobronchomalacia
Eligibility:
All Genders
Brief Summary
The primary aim of this study is to determine if work of breathing estimated using swing Edi will be improved following initiation of bethanechol in infants with tracheobronchomalacia. The investigato...
Detailed Description
Tracheobronchomalacia (TBM) is characterized by dynamic airway collapse resulting from flaccidity of smooth trachealis muscles, and the incidence in infants has been estimated to be as high as 16-50%....
Eligibility Criteria
Inclusion
- Infants with a diagnosis of tracheobronchomalacia by dynamic computed tomography and showing \> 50% cross-sectional diameter collapse at 40 to 60 post menstrual age and for whom will be treatment with bethanechol in level IV center Neonatal Intensive Care Unit.
Exclusion
- Infants with diagnosis of tracheobronchomalacia by dynamic computed tomography with \< 50% cross-sectional diameter collapse at 40 to 60 post menstrual age, or infants in which the medical team has not made the decision to start bethanechol.
- Patients with fixed tracheomalacia or bronchomalacia due to external compression of airways.
Key Trial Info
Start Date :
August 11 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
June 30 2024
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT05299008
Start Date
August 11 2022
End Date
June 30 2024
Last Update
January 30 2024
Active Locations (1)
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1
Arkansas Children's Hospital
Little Rock, Arkansas, United States, 72202