Status:

NOT_YET_RECRUITING

HIPEC Combined Gastrectomy in Patients With Advanced Gastric Cancer Received Neoadjuvant Chemotherapy

Lead Sponsor:

Zhixin Cao

Conditions:

Gastric Cancer

Peritoneal Metastases

Eligibility:

All Genders

18-75 years

Phase:

PHASE2

PHASE3

Brief Summary

Patients with stage cT3-4N+M0 gastric cancer were recommended to receive neoadjuvant chemotherapy before radical surgery in terms of the eradication of micrometastasis in addition to local control, hi...

Eligibility Criteria

Inclusion

  • histologically proven adenocarcinoma of stomach
  • stage cT3-4N+M0
  • no involvement of esophagus \> 3 cm
  • ECOG (Eastern Cooperative Oncology Group) : 0\~1
  • no previous chemotherapy or radiotherapy for any malignancy
  • no previous surgery for GC excluding endoscopic mucosal resection or endoscopic submucosal dissection
  • Signed the Informed Consent Form

Exclusion

  • Serious diseases that are difficult to control
  • Severe hepatic and renal dysfunction
  • Abnormal coagulation
  • The presence of other serious physical or mental illness or laboratory abnormalities may increase the risk of participating in the study, or interfere with the results of the study, as well as the patients who the investigator believes are not suitable for participating in the study

Key Trial Info

Start Date :

January 1 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 31 2028

Estimated Enrollment :

200 Patients enrolled

Trial Details

Trial ID

NCT05300945

Start Date

January 1 2023

End Date

December 31 2028

Last Update

December 6 2022

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