Status:
UNKNOWN
Intra-articular Injection of Lidocaine in Inflammatory Arthritis
Lead Sponsor:
Guy's and St Thomas' NHS Foundation Trust
Conditions:
Inflammatory Arthritis
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
To assess the contributions of peripheral neurons to joint pain, the investigators plan to ask patients to rate the pain in their chosen joint before and after an injection of local anaesthetic (lidoc...
Detailed Description
Patients will be randomised to receive joint injection of either lidocaine plus steroid or, as a control, just steroid injection. Pain scores (visual analogue score 0-10) in the chosen joint will be c...
Eligibility Criteria
Inclusion
- Diagnosis of peripheral inflammatory joint disease
- Reporting current NRS pain ≥3 on a 0-10 scale
- Only perform this test when an aspiration and joint injection is clinically indicated and would be given as part of routine care
Exclusion
- Under 18 years of age
- Unable or unwilling to provide informed written consent
- Unable to comply with study protocols
- Pregnancy and breastfeeding
- If the chosen joint has been aspirated or injected in the preceding 3 months
- Presence of joint damage in chosen joint as assessed by Professor Kirkham on x-ray of the chosen joint (as joint damage itself can stimulate peripheral nociceptors)
Key Trial Info
Start Date :
April 18 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
October 18 2022
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT05302232
Start Date
April 18 2022
End Date
October 18 2022
Last Update
March 31 2022
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