Status:
RECRUITING
A Prospective Cluster-Randomized, Controlled Crossover Trial to Validate an Electronic "Resistance Calculator"
Lead Sponsor:
Dror MarChaim, MD
Collaborating Sponsors:
Hadassah Medical Organization
Conditions:
Sepsis
Eligibility:
All Genders
18+ years
Brief Summary
Primary objective: \- Our aim is to validate the "Shamir Resistance Calculator" in a prospective crossover trial, in order to shorten the time to initiation of appropriate antimicrobials among hospit...
Detailed Description
2.1 List the clinical hypotheses. * Primary hypothesis: The "Shamir Resistance Calculator" will shorten the time to initiation of appropriate antimicrobials among hospitalized septic patients. * Seco...
Eligibility Criteria
Inclusion
- Adult patients (age\>18 years)
- Patients who are hospitalized at Shamir MC or at Hadassah Medical Organization during the study period.
- o Patients admitted to the ER and later-on discharged home, or discharged from the ER to a different facility, will be excluded as it will not enable us to follow all the designated outcomes.
- Patients for which antibiotic treatment was initiated, empirically, due to acute sepsis.
- Patients for which antibiotics were initiated as part of a main-consolidative regimen, or as part of a pre-emptive regimen, will not be included in the study.
- Sepsis will be defined in accordance to established criteria1.
Exclusion
- \-
Key Trial Info
Start Date :
July 3 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
January 1 2025
Estimated Enrollment :
1500 Patients enrolled
Trial Details
Trial ID
NCT05304221
Start Date
July 3 2023
End Date
January 1 2025
Last Update
July 31 2024
Active Locations (2)
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1
Shamir Medical Center (Assaf Harofeh)
Be’er Ya‘aqov, Israel, 70300
2
Hadassah Medical Organization
Jerusalem, Israel, 91120