Status:

WITHDRAWN

Randomized Assessment of Antibiotic Prophylaxis Prior to Port Placement

Lead Sponsor:

Dartmouth-Hitchcock Medical Center

Conditions:

Vascular Access Ports

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

A randomized, double blind, placebo-controlled clinical trial assessing the utility of antibiotic prophylaxis prior to Totally Implanted Venous Access Device (TIVAD) insertion.

Detailed Description

To assess the effectiveness of peri-procedural antibiotic prophylaxis in the reduction of TIVAD placement-related infection, study will compare placebo (normal saline (0.9% NaCl)) 50 cc IV 1:1 to the ...

Eligibility Criteria

Inclusion

  • Adult patients requiring TIVAD insertion for long-term central venous access
  • Patients able to give informed consent to participate in the study.

Exclusion

  • taking long-term antibiotics
  • unable to give consent to participate in the study
  • Patients that have a known infection at time of the procedure (as documented in e-DH).
  • Patients with a planned surgical procedure within 30 days of initial TIVAD insertion.
  • Patients that are currently on antibiotics or have received antibiotics within the last week.
  • Patients with allergies to cefazolin.
  • Patients with an absolute neutrophil count of less than 500/mm3
  • Women who are pregnant.

Key Trial Info

Start Date :

January 1 2024

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2027

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT05304871

Start Date

January 1 2024

End Date

December 1 2027

Last Update

April 26 2024

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