Status:
UNKNOWN
Retinal, Cerebral and Vascular Precursor Markers of Cerebral Small Vessel Disease.
Lead Sponsor:
University Hospital, Bordeaux
Collaborating Sponsors:
University of Bordeaux
Conditions:
Cerebral Small Vessel Diseases
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Cognitive impairment and dementia are primarily due to a combination of vascular brain injury and neurodegenerative lesions. The vascular component is now recognized as a major contributor to the path...
Detailed Description
Small Vessel Disease is most often covert i.e detectable only on brain images without being associated with a clinical stroke. Covert SVD (cSVD) is highly prevalent in older persons from the general p...
Eligibility Criteria
Inclusion
- Young adults from the i-Share cohort will be included in the study:
- having signed the informed consent form of the MRi-Share sub-study,
- having signed the informed consent form for the bio-Share sub-study,
- for whom brain MRI images and for whom the results of the genome-wide genetic association study (GWAS) are of good quality
- having signed freely, an informed and written consent for this study (at the latest on the day of inclusion and before any examination required by the research),
- being affiliated with social security.
Exclusion
- Will not be included in the study:
- participants with severe myopia greater than -6 dioptres
- participants with known allergy to Tropicamide (Mydriaticum®)
Key Trial Info
Start Date :
June 7 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 7 2024
Estimated Enrollment :
206 Patients enrolled
Trial Details
Trial ID
NCT05305144
Start Date
June 7 2021
End Date
June 7 2024
Last Update
October 6 2023
Active Locations (1)
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1
CHU de Bordeaux
Bordeaux, France, 33076