Status:

RECRUITING

Molecular Analysis of Endoscopic Cytology Samples Supernatant in Pulmonary Nodules

Lead Sponsor:

University Hospital, Toulouse

Conditions:

Lung Cancer

Lung; Node

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Lung cancer screening is based on low dose CT scan (LDCT), a highly sensitive but poorly specific tool. Complementary specific approaches are thus strongly needed, among which cell-free DNA (cfDNA) g...

Detailed Description

Tumor biopsy is often required to characterize indeterminate nodules. Radial endobronchial ultrasound (rEBUS) bronchoscopy is often used due to a low rate of complications but its sensitivity is limit...

Eligibility Criteria

Inclusion

  • rEBUS bronchoscopy planned for one, two or three ≤ 20 mm nodule
  • World Health Organization (WHO) Performance status 0-3
  • Informed signed consent
  • Patient affiliated or beneficiary of a social security scheme (Social Security or Universal Medical Coverage).

Exclusion

  • Lung cancer diagnosed before the date of the procedure
  • Lung cancer strongly suspected due to mediastinal or extra thoracic lesions
  • Patient under State Medical Assistance
  • Patient deprived of liberty on administrative or judicial decision, or patient under guardianship, curators or safeguard of justice

Key Trial Info

Start Date :

April 8 2022

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2026

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT05306912

Start Date

April 8 2022

End Date

December 1 2026

Last Update

July 3 2024

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Toulouse University Hospital

Toulouse, Occitanie, France, 31300