Status:

UNKNOWN

HRD and Resistance to PAPPi in EOC Patients

Lead Sponsor:

Lei Li

Conditions:

Epithelial Ovarian Cancer

Homologous Recombination Deficiency

Eligibility:

FEMALE

18+ years

Brief Summary

The association between homologous recombination (HR) gene mutations and homologous recombination deficiency (HRD) status in Chinese epithelial ovarian cancer (EOC) patients has been investigated in p...

Eligibility Criteria

Inclusion

  • Aged 18 years or older
  • Pathological confirmation of epithelial ovarian cancer
  • With available tumor tissues
  • Given consents to participate the study
  • With detailed follow-up outcomes

Exclusion

  • Not meeting all of the inclusion criteria
  • Declining to accept PARPi as maintenance therapy after the major treatment for cancer

Key Trial Info

Start Date :

March 26 2022

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

March 26 2025

Estimated Enrollment :

400 Patients enrolled

Trial Details

Trial ID

NCT05310370

Start Date

March 26 2022

End Date

March 26 2025

Last Update

April 4 2022

Active Locations (1)

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1

Lei Li

Beijing, Beijing Municipality, China, 100730