Status:

WITHDRAWN

Strata EXPress™: A Study Using StrataEXP™ to Identify RNA-Expression Biomarkers in Advanced Cancer Patients

Lead Sponsor:

Strata Oncology

Conditions:

Cancer

Eligibility:

All Genders

18+ years

Brief Summary

The primary goal of this study is to identify patients with RNA expression profiles consistent with eligibility requirements for therapeutic clinical trials across solid tumors. Left-over tumor tissue...

Detailed Description

The primary goal of this study is to identify patients with RNA expression profiles consistent with eligibility requirements for therapeutic clinical trials across solid tumors. Left-over tumor tissue...

Eligibility Criteria

Inclusion

  • Must be ≥18 years of age,
  • Participant must have pathologically confirmed advanced, metastatic, or recurrent solid tumor,
  • Measurable disease,
  • Eastern Cooperative Oncology Group (ECOG) performance status score of 0-2,
  • Participant must meet at least 1 of the following:
  • Is/has not adequately responded to standard therapy, or
  • For whom no life-extending standard therapy exists, or
  • Who decline standard therapy, or
  • In the opinion of the investigator, is not a candidate for or would be unlikely to tolerate or derive significant clinical benefit from standard therapy
  • Adequate cardiac, bone marrow, organ function \& laboratory parameters as determined by the treating physician for potential participation in a clinical trial,
  • Leftover formalin-fixed, paraffin-embedded (FFPE) tumor tissue available for StrataEXP testing

Exclusion

  • Females who are pregnant or nursing,
  • History of stroke including transient ischemic attack (TIA) or acute myocardial infarction within 4 months of enrollment,
  • Any other clinically significant medical condition that, in the opinion of the treating physician, makes participation in a clinical trial undesirable, including but not limited to ongoing or active infection, significant uncontrolled hypertension, or severe psychiatric illness.

Key Trial Info

Start Date :

February 6 2023

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

February 22 2024

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT05312307

Start Date

February 6 2023

End Date

February 22 2024

Last Update

February 26 2024

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