Status:
UNKNOWN
Exercise Fatiguability in Older Adults: The Protective Effects of Dietary Nitrate Supplementation
Lead Sponsor:
Marquette University
Conditions:
Aging
Eligibility:
All Genders
60-90 years
Phase:
NA
Brief Summary
Vascular and skeletal muscle function decline with age and are associated with decreased nitric oxide (NO) bioavailability. Dietary nitrate supplementation in the form of beet root juice increases NO ...
Eligibility Criteria
Inclusion
- Healthy men and women ≥ 60 years old
Exclusion
- body mass index ≥40 kg/m2;
- type 1 or type 2 diabetes or HbA1c \>6.5%
- uncontrolled hypertension;
- active cancer, cancer in remission, or having received treatment for any form of cancer in the previous five years;
- coronary artery disease;
- cardiovascular disease (e.g., PAD, PVD);
- abnormal and untreated thyroid function;
- chronic and/or regular nonsteroidal anti-inflammatory drugs (NSAID) consumption,
- tobacco use (includes smoking);
- any condition that presents a limitation to exercise (e.g., severe arthritis, COPD, neuromuscular disorder, moderate or severe cognitive impairment, Alzheimer's Disease, severe untreated sleep apnea).
Key Trial Info
Start Date :
May 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2023
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT05313490
Start Date
May 1 2022
End Date
December 31 2023
Last Update
August 24 2022
Active Locations (1)
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1
Marquette University
Milwaukee, Wisconsin, United States, 53233