Status:

RECRUITING

Moderate Hypofractionated Boost to the Prostate With Pelvic RT in High Risk Prostate Cancer

Lead Sponsor:

University Health Network, Toronto

Conditions:

Prostate Cancer

Eligibility:

MALE

18+ years

Phase:

NA

Brief Summary

This is a single-arm phase II prospective trials that is recruiting 100 participants. The study population that is being investigated are patients with localized high-risk or node-positive prostate ca...

Eligibility Criteria

Inclusion

  • Age \> 18 years.
  • Able to provide informed consent.
  • Histologic diagnosis of prostate adenocarcinoma.
  • ECOG performance status 0-1.
  • High-risk localized disease by NCCN criteria (\>cT3, Grade group \>4, or PSA \>20 ng/mL) or clinical N1 disease.
  • Clinical M0 by conventional imaging (computed tomography (CT) and bone scan (BS)) and/or molecular imaging (prostate specific membrane antigen (PSMA)- positron emission tomography (PET))

Exclusion

  • Prior pelvic radiotherapy.
  • Contraindications to radiotherapy

Key Trial Info

Start Date :

July 18 2022

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

July 1 2030

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT05313815

Start Date

July 18 2022

End Date

July 1 2030

Last Update

June 18 2024

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Princess Margaret Cancer Center

Toronto, Ontario, Canada, M5G 2M9