Status:
UNKNOWN
Treatment With SGLT-2 Inhibitor for Postoperative Hyperglycemia in Acute Abdominal Surgery - a Randomized Trial
Lead Sponsor:
Zealand University Hospital
Conditions:
Postoperative Hyperglycemia
Stress Hyperglycemia
Eligibility:
All Genders
18-85 years
Phase:
PHASE2
Brief Summary
The aim of the study is to investigate the effect of an SGLT-2 inhibitor on postoperative hyperglycemia after acute abdominal surgery in patients without diabetes
Eligibility Criteria
Inclusion
- \- Admitted to the ward after acute abdominal surgery (ASAP patient at Slagelse Hospital, OMEGA patient at Zealand University Hospital)
- At least two independent measurements of blood glucose above 7.7mmol/l within the first 48 hours after surgery
- Age of 18 to 85
- Must be able to understand and sign informed content
Exclusion
- Patients diagnosed with diabetes mellitus
- Impaired kidney function (eGFR \< 45mL/min)
- Severe liver disease (defined as transaminases above X 3 normal levels)
- Acute pancreatitis within the last two months or a history of chronic pancreatitis
- Participation in another pharmacological intervention trial
- Predictable poor compliance (for instance mentally impaired)
- Pregnancy or lactation (fertile women must have a negative serum or urine pregnancy test to participate)
- Allergy to study medication
Key Trial Info
Start Date :
June 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2023
Estimated Enrollment :
24 Patients enrolled
Trial Details
Trial ID
NCT05314725
Start Date
June 1 2022
End Date
June 1 2023
Last Update
April 6 2022
Active Locations (0)
Enter a location and click search to find clinical trials sorted by distance.
No Results Found
We couldn’t find results for the location/zipcode entered or within the selected range. Please check your input or adjust your search.