Status:
COMPLETED
The Effects of Hydration on Gut Health and Thinking
Lead Sponsor:
University of Illinois at Urbana-Champaign
Collaborating Sponsors:
Division of Nutritional Sciences, University of Illinois at Urbana-Champaign
Conditions:
Dehydration
Cognitive Change
Eligibility:
All Genders
19-50 years
Phase:
NA
Brief Summary
The central hypothesis is that improving hydration through increased water consumption will change the relative abundance of mucolytic bacteria found in the stool. Therefore the specific aims are 1) t...
Detailed Description
A single arm 3-week hydration intervention will be employed where participants increase their water consumption to 2 (F) or 2.5(M) liters per day which is approximately 70% of the AI for daily water c...
Eligibility Criteria
Inclusion
- 19-50 years of age
- 5-34.49 kg/m2
- 24-hour UOsm above 500 mOsm/kg
- No antibiotic use over the past 3 months
- Absence of metabolic diseases and use of diuretics
- Agree to maintain typical diet intake (e.g., dietary fiber) patterns during intervention
- Avoid consuming prebiotic and probiotic supplements during study participation
- Not pregnant
- Agree to follow the study protocol
Exclusion
- \<19 or \>50 years of age
- \<18.5 or \>34.49 kg/m2
- 24-hour UOsm \<500 mOsm/kg
- Antibiotic use over the past 3 months
- Metabolic diseases and use of diuretics
- Not agree to maintain typical diet intake (e.g., dietary fiber) patterns for the duration of the
- intervention
- Not agree with avoiding consuming prebiotic and probiotic supplements during study participation
- Pregnant
- Not agree to follow study protocol
Key Trial Info
Start Date :
August 23 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 29 2022
Estimated Enrollment :
23 Patients enrolled
Trial Details
Trial ID
NCT05315531
Start Date
August 23 2021
End Date
July 29 2022
Last Update
January 11 2024
Active Locations (1)
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1
University of Illinois at Urbana-Champaign
Urbana, Illinois, United States, 61801