Status:
RECRUITING
Clinical Validation of DystoniaNet Deep Learning Platform for Diagnosis of Isolated Dystonia
Lead Sponsor:
Massachusetts Eye and Ear Infirmary
Conditions:
Dystonia
Drug Induced Dystonia
Eligibility:
All Genders
Phase:
NA
Brief Summary
This research involves retrospective and prospective studies for clinical validation of a DystoniaNet deep learning platform for the diagnosis of isolated dystonia.
Detailed Description
Isolated dystonia is a movement disorder of unknown pathophysiology, which causes involuntary muscle contractions leading to abnormal, typically patterned, twisting movements and postures. A significa...
Eligibility Criteria
Inclusion
- Inclusion criteria:
- Males and females of diverse racial and ethnic backgrounds, with age across the lifespan;
- Patients will have at least one of the forms of dystonia, including focal dystonia (e.g., laryngeal, cervical, oromandibular, blepharospasm, focal hand, musicians), segmental dystonia, or generalized dystonia;
- Patients will have other movement disorders (Parkinson's disease, essential tremor, dyskinesia, myoclonus) and other non-neurological conditions (tic disorders, torticollis, ulnar nerve entrapments, temporomandibular disorders, dysphonia) that mimic dystonic symptoms.
- Exclusion criteria:
- Patients who are incapable of giving informed consent;
- Patients who are unable to undergo brain MRI due to the presence of certain tattoos and ferromagnetic objects in their bodies (e.g., implanted stimulators, surgical clips, prosthesis, artificial heart valve) that cannot be removed or due to pregnancy or breastfeeding at the time of the study.
Exclusion
Key Trial Info
Start Date :
June 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
April 30 2028
Estimated Enrollment :
1000 Patients enrolled
Trial Details
Trial ID
NCT05317390
Start Date
June 1 2022
End Date
April 30 2028
Last Update
December 2 2025
Active Locations (1)
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1
Massachusetts Eye and Ear Infirmary
Boston, Massachusetts, United States, 02114