Status:

COMPLETED

Incidence and Risk Factors of Weaning-induced Cardiac Dysfunction: Results From a Multicenter, Observational Study

Lead Sponsor:

Bicetre Hospital

Conditions:

Weaning Failure

Weaning-induced Pulmonary Edema

Eligibility:

All Genders

18+ years

Brief Summary

During weaning from mechanical ventilation, the shift from positive to negative pressure ventilation may be responsible for a cardiac dysfunction that can lead to the development of pulmonary oedema (...

Detailed Description

During weaning from mechanical ventilation, the shift from positive to negative pressure ventilation may be responsible for a cardiac dysfunction that can lead to the development of pulmonary oedema (...

Eligibility Criteria

Inclusion

  • Age ≥ 18 years.
  • Social coverage from health insurance (in France).
  • Decision of the attending physicians to perform an SBT.

Exclusion

  • Presence of tracheostomy (in this case at the end of the test the patient could be connected to the ventilator, even in case of positivity of the weaning test. Thus, it is not possible to test the absence of reintubation at 48 hours, which is one of the criteria defining the success of weaning).
  • Refusal of the patient or, if the case, one of the relatives to participate to the study.

Key Trial Info

Start Date :

July 1 2019

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

June 3 2022

Estimated Enrollment :

500 Patients enrolled

Trial Details

Trial ID

NCT05318261

Start Date

July 1 2019

End Date

June 3 2022

Last Update

November 16 2022

Active Locations (1)

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1

Medical Intensive Care Unit

Le Kremlin-Bicêtre, France