Status:

RECRUITING

China Gender-affirming Hormone Therapy Study

Lead Sponsor:

Peking University Third Hospital

Collaborating Sponsors:

Tsinghua University

Conditions:

Transgender

Gender Incongruence

Eligibility:

All Genders

18-40 years

Brief Summary

Data about transgender medical care, especially the gender-affirming hormone therapy (GAHT) is extremely insufficient in China. Few evidence exists in the physical and psychological effects of the hor...

Detailed Description

CGAHT will be conducted in one of the main transgender medical centers in Chinese mainland. Participants who are seeking for the start of GAHT will be enrolled from clinical visitors. Before GAHT, par...

Eligibility Criteria

Inclusion

  • Transgender men and women
  • Meet criteria of Diagnostic and Statistical Manual of Mental Disorders (Fifth Edition) for gender dysphoria
  • Aged between 18 to 40 years
  • People desire to start the GAHT
  • No previous history of gender-affirming interventions
  • Having full ability to make informed consent
  • Dextromanual

Exclusion

  • Disorders of sex development
  • Who has fertility demand but have not made fertility preservation
  • With contradictions of GAHT
  • Comorbid diseases are not under control
  • Alcohol or drug abuse
  • Hormonal and chromosomal disorders
  • History of gender affirming surgery
  • Current psychiatric disorders
  • History of brain trauma or neurological pathologies
  • Current use of medications with psychotropic effects within two weeks (antipsychotic or antiepileptic agents, lithium, benzodiazepines or opioid analgesics)
  • Claustrophobia
  • Implanted metal and medical devices (pacemakers, ceramic teeth, etc.),
  • Tattoos or eyebrow tattooing (heavy metal dye)

Key Trial Info

Start Date :

April 16 2022

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 31 2028

Estimated Enrollment :

240 Patients enrolled

Trial Details

Trial ID

NCT05318755

Start Date

April 16 2022

End Date

December 31 2028

Last Update

November 7 2024

Active Locations (1)

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1

Peking University Third Hospital

Beijing, Beijing Municipality, China, 100191