Status:

RECRUITING

Evaluate DF-003 in ex Vivo Assays Using Peripheral Blood Mononuclear Cell From Subjects With ROSAH Syndrome

Lead Sponsor:

Hospices Civils de Lyon

Conditions:

Unrecognized Condition

Eligibility:

All Genders

18+ years

Brief Summary

Alpha-1 kinase (ALPK1) has been reported as a potential causative gene for ROSAH Syndrome. Genetic variants including T237M have been found in ROSAH Syndrome patients. Our in-house study has found th...

Eligibility Criteria

Inclusion

  • Male or female aged over 18
  • Patient with ROSAH syndrome with the confirm T237M mutation

Exclusion

  • person under legal protection or under protectives measures
  • person unable to express consent
  • person in emergency situation (vital or not)
  • person infected by Human Immunodeficiency Virus and/or Hepatitis B Virus and/or Hepatitis C Virus

Key Trial Info

Start Date :

September 6 2022

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

May 6 2028

Estimated Enrollment :

4 Patients enrolled

Trial Details

Trial ID

NCT05319132

Start Date

September 6 2022

End Date

May 6 2028

Last Update

August 8 2025

Active Locations (5)

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Page 1 of 2 (5 locations)

1

Hôpital Nord Croix Rousse

Lyon, Auvergne-Rhône-Alpes, France, 69004

2

service de Genetique - Institut de Biologie Santé PBH-IBS

Angers, France, 49000

3

Hôpital de la Pitié Salpétrière

Paris, France, 75013

4

Service D'ophtalmologie

Reims, France, 51000