Status:
UNKNOWN
The Effect of Intra Operative Dexmedetomidine in Prevention of Early Postoperative Atrial Fibrillation
Lead Sponsor:
Kasr El Aini Hospital
Conditions:
Postoperative Atrial Fibrillation
Eligibility:
All Genders
18-70 years
Phase:
PHASE1
Brief Summary
The incidence of atrial fibrillation (AF) after lung resection varies between 12% and 30% after lobectomy and 23%-67% after pneumonectomy. The average time of onset of AF after lung resection is 2-3 d...
Detailed Description
This a randomized control trial is designed to include (350) patients ASA physical status II patients ranging from(18) to(70)years old scheduled for thoracic non cardiac surgeries Patients meeting th...
Eligibility Criteria
Inclusion
- Gender both males and females
- ASA Class II
- Age 18-70 years
- Patients undergoing thoracic non cardiac surgeries(lobectomy, pneumonectomy, and esophagectomy).
Exclusion
- A. Hypersensitivity or known allergy to dexmedetomidine. b.Patients with Sick-sinus orWolff-Parkinson-White syndromes; atrioventricular block atrial fibrillation within 30 days; a permanent pacemaker; used amiodarone or dexmedetomidine within30 days.
- c. Patients with echocardiographic finding of an ejection fraction \<30% and left atrial diameter more than 45mm and use of beta blockers or statins.
- d. Liver and renal impairment(elevated liver enzymes (ALT, AST two to three fold), CRF ) e .Emergency operations ,video assisted thoracic surgeries and operation for spontaneous pneumothorax
Key Trial Info
Start Date :
April 15 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 1 2022
Estimated Enrollment :
350 Patients enrolled
Trial Details
Trial ID
NCT05320705
Start Date
April 15 2022
End Date
September 1 2022
Last Update
May 10 2022
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Kasr Alainy, Cairo University
Cairo, Egypt, 202