Status:

RECRUITING

Patient Derived Preclinical Models

Lead Sponsor:

Mayo Clinic

Conditions:

Cancer

Eligibility:

All Genders

18+ years

Brief Summary

Study goal is to collect tumor specimens that may inform cancer biology to eventually improve outcomes for patients with cancer. This proposal represents a highly collaborative effort to support cance...

Detailed Description

The objective of this study is to collect tumor specimens (tumor tissues, matched normal tissue when possible, and 50 mL of blood) that may inform cancer biology to eventually improve outcomes for pat...

Eligibility Criteria

Inclusion

  • 18 years of age and older
  • Patient is a good medical candidate for a standard of care or research biopsy or surgical procedure to obtain tissue

Exclusion

  • Uncontrolled concurrent illness including psychiatric illness, or situations that would limit compliance with the study requirements or the ability to willingly give written informed consent
  • Institutionalized or incarcerated patients
  • Inaccessible tumor for biopsy or patient does not have tumor tissue available for research use
  • Biopsy must not be considered more than minimal risk to the patient.
  • Have a contraindication to percutaneous biopsy including:
  • Significant coagulopathy that cannot be adequately corrected.
  • Severely compromised cardiopulmonary function or hemodynamic instability.
  • Lack of a safe pathway to the lesion per the interventional radiologist.
  • Inability of the patient to cooperate with, or to be positioned for, the procedure.

Key Trial Info

Start Date :

April 6 2022

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

March 31 2028

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT05324553

Start Date

April 6 2022

End Date

March 31 2028

Last Update

May 2 2025

Active Locations (1)

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Mayo Clinic in Rochester

Rochester, Minnesota, United States, 55905