Status:
UNKNOWN
Functional and Electromyographical Changes After PRP or Dextrose Injection in Chronic Lateral Epicondylitis
Lead Sponsor:
Chen Yueh
Conditions:
Tennis Elbow
Eligibility:
All Genders
20-65 years
Phase:
PHASE3
Brief Summary
The purpose of this study is to find out functional and electromyographical changes after platelet rich plasma and dextrose injection in chronic lateral epicondylitis.
Detailed Description
Both platelet rich plasma (PRP) and dextrose treat chronic lateral epicondylalgia (CLE), mechanically by enhancing tendon cell proliferation, differentiation, and maturation. In fact, hypertonic gluco...
Eligibility Criteria
Inclusion
- The control group
- Inclusion criteria:
- 1\. The ages of 20-65 years without any neurological or muscular disease.
- Exclusion criteria:
- 1\. Systemic disorders such as diabetes, rheumatoid arthritis, or hepatitis
- The treatment group (Experimental group)
- Patients with lateral epicondylitis in the elbow (age: 20-65 years old)
- Pain unresponsive to 1 of 3 conventional therapy programs (local steroid injections, physical/occupational therapy, nonsteroidal anti-inflammatory medications)
- History of elbow pain for at least 3 months
- Elbow pain at least 50 mm/100 mm using a visual analog scale (VAS)
Exclusion
- Healthy population between the ages of 20-65 years
- Pregnancy
- History of bleeding disorder, anemia, or any blood disorder (such as Hemoglobin \<11 g/dL; Hematocrit \<33%; Platelet count outside of the normal range of 150 to 400 x1000/u)
- Active bilateral elbow tendinosis within 4 weeks, previous surgery for elbow tendinosis or fracture of the affected elbow
- History of arthritis or, cervical radiculopathy, carpal tunnel syndrome on the affected side within 1 year before randomization
- Systemic disorders such as diabetes, rheumatoid arthritis, or hepatitis
- Uncooperative patient or patient with neurological disorders who is incapable of following directions or who is predictably unwilling to return for follow-up examinations
- Hypothyroidism
- Received local steroid injections within 6 weeks, physical/occupational therapy within 4 weeks, or non- steroidal anti-inflammatory medications within 1 week
- Intolerance to acetaminophen
Key Trial Info
Start Date :
May 25 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2022
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT05326763
Start Date
May 25 2021
End Date
December 31 2022
Last Update
April 14 2022
Active Locations (1)
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1
Chen Yueh
Tainan, Taiwan, 72152