Status:

COMPLETED

An Exploratory Investigation of Dietary Supplementation and the Effect on Common Symptoms of Hormonal Imbalance

Lead Sponsor:

Semaine Health

Collaborating Sponsors:

Citruslabs

Conditions:

Hormone Disturbance

Eligibility:

FEMALE

18-55 years

Phase:

NA

Brief Summary

This is an open-label observational trial to study the effectiveness of a commercial dietary supplement and its effect on common symptoms of normal menstrual discomfort.

Detailed Description

This is an open-label observational trial to study the effectiveness of a commercial dietary supplement and its effect on common symptoms of normal menstrual discomfort. It is hypothesized that the d...

Eligibility Criteria

Inclusion

  • Provision of signed and dated informed consent form
  • Stated willingness to comply with all study procedures and availability for the duration of the study
  • Female, aged 18-55 (roughly 75% 18-38 and 25% 45-55)
  • Ability to take oral medication and be willing to adhere to the dietary supplement regimen (2 capsules per day)
  • Willing to fast overnight (12+ hours) prior to the blood collection, and to perform an at-home fingerprick blood test
  • Moderate self-reported discomfort related to perceived hormone imbalance. Participants must answer B or C on at least 3 of the following questions:

Exclusion

  • Current use of medication for high blood pressure or for blood thinning
  • Diabetic, or on medication such as Metformin or Acarbose
  • Pregnancy, breastfeeding, or attempting to become pregnant during study
  • Known allergic reactions to components of the dietary supplement (sunflower oil, passionflower, berberine, or grape seed extract )
  • Has exercised 3+ times per week of 30 minutes or more per session on average over the past 6 month
  • On a ketogenic or vegan diet for more than the past 30 days
  • If hormonal birth control, cannot stop during the duration of the study.

Key Trial Info

Start Date :

March 15 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 15 2022

Estimated Enrollment :

45 Patients enrolled

Trial Details

Trial ID

NCT05328609

Start Date

March 15 2022

End Date

June 15 2022

Last Update

October 26 2022

Active Locations (1)

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Citruslabs

Santa Monica, California, United States, 90404