Status:

COMPLETED

Examination of Muscle Stiffness, Tenderness and Pressure Pain Thresholds During a Cycle of Botulinum Toxin A Treatment in Chronic Migraine Patients

Lead Sponsor:

Danish Headache Center

Conditions:

Chronic Migraine

Eligibility:

All Genders

18+ years

Brief Summary

Preventive treatment with botulinum toxin A injections is standard care for chronic migraine and follows the PREEMPT protocol. Patients are injected at 31 locations in the frontal, corrugator and proc...

Detailed Description

Study population The population considered for inclusion in the study is patients with CM treated with botulinum toxin A injections every third months at DHC. This is an observational study, and incl...

Eligibility Criteria

Inclusion

  • Patients being treated (or are starting treatment) with botulinum toxin A injections in the clinical setting at the DHC. Treatment is based on confirmed CM-diagnosis according to the ICHD-III (4), diagnosed by headache specialists at DHC
  • Aged 18 - 65 years
  • Able to sign an informed consent

Exclusion

  • Medication overuse headache
  • Known cervical disorders, e.g. cervical spine disc prolapses, whiplash or spinal stenosis
  • Change in other pharmacological preventive medication during the study period. Stable pharmacological preventive medication is allowed.

Key Trial Info

Start Date :

May 1 2021

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 1 2022

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT05328687

Start Date

May 1 2021

End Date

December 1 2022

Last Update

January 29 2025

Active Locations (1)

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Danish Headache Center

Glostrup Municipality, Denmark, 2600