Status:
UNKNOWN
Does Genetic Susceptibility for Bleeding Affect Quantitative Faecal Immunochemical Test (qFIT) Results?
Lead Sponsor:
University of Edinburgh
Collaborating Sponsors:
Royal College of Surgeons of Edinburgh
Conditions:
Colon Cancer
Colorectal Cancer
Eligibility:
All Genders
16+ years
Brief Summary
Quantitative faecal immunochemical testing (qFIT) is used to test for blood within faeces that cannot always be visible. The presence of blood in the stool has been shown to be a finding where there m...
Detailed Description
Quantitative faecal immunochemical testing (qFIT) measures the presence of haemoglobin within faeces. It is an immunoassay based method, measuring the globin portion of human haemoglobin or its early ...
Eligibility Criteria
Inclusion
- Patients who were symptomatic at the time of referral
- Returned at least one qFIT sample
- Underwent a complete colonoscopy, which did not identify any pathology
- Willing to provide a saliva sample for genetic analysis
- Are able to consent to the study
Exclusion
- Age \< 18
- Previous colorectal cancer
- Ongoing colonic polyp surveillance
- Known inflammatory bowel disease
- Taking anticoagulant medication (Aspirin, clopidogrel, warfarin or NOAC)
- History of liver disease or known bleeding disorder
- Incomplete colonoscopy
- Unable to consent to the study
Key Trial Info
Start Date :
June 1 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
March 1 2024
Estimated Enrollment :
150 Patients enrolled
Trial Details
Trial ID
NCT05329870
Start Date
June 1 2022
End Date
March 1 2024
Last Update
April 15 2022
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