Status:
UNKNOWN
Epidemiology of Neurological Complications to Nitrous Oxide Poisoning
Lead Sponsor:
Centre Hospitalier de Saint-Denis
Conditions:
Neurology Department
Eligibility:
All Genders
16+ years
Brief Summary
N2O inactivates vitamin B12, impairing its ability to act as a cofactor of methionine synthase. In addition, the elimination of vitamin B12 is increased. Neurological damage is similar to that describ...
Eligibility Criteria
Inclusion
- Adult patient (≥16 years)
- Hospitalized or having consulted with the departments of Neurology or Internal Medicine for neurological phenomena related to the consumption of N2O. The neurological phenomena included are usually: neuropathies or myelopathies, However, the existence of other neurological or psychiatric signs is not a factor of exclusion: for example, headaches or cognitive or psychiatric disorders with acute onset.
- Exposure to N2O for recreational or medical reasons (Meopa anesthesia).
- Lack of alternative diagnosis other than N2O poisoning
- Consultation for neurological disorders between 01/01/2018 and 31/12/2021
Exclusion
- Minor subjects or subjects subject to a legal protection measure (guardianship, curators) during the consultation.
- Refusal to include in a study explained in the file
- Absence of N2O consumption during the 6 months preceding the appearance of signs
Key Trial Info
Start Date :
April 10 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
August 31 2022
Estimated Enrollment :
135 Patients enrolled
Trial Details
Trial ID
NCT05329909
Start Date
April 10 2022
End Date
August 31 2022
Last Update
August 11 2022
Active Locations (1)
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1
Hôpital DELAFONTAINE
Saint-Denis, Île-de-France Region, France, 93200