Status:
COMPLETED
Five Years Follow-up of Neurological Outcome After Minimally Invasive Cardiac Surgery
Lead Sponsor:
Jessa Hospital
Conditions:
Surgery
Postoperative Cognitive Dysfunction
Eligibility:
All Genders
18+ years
Brief Summary
A monocenter observational study will be started to investigate postoperative cognitive dysfunction 5 years after minimally invasive cardiac surgery. Postoperative cognitive dysfunction will be evalua...
Detailed Description
Neurologic complications after cardiac surgery are a major cause of morbidity, prolonged hospital stay and increased costings. In selected cases, postoperative neurologic damage leads to permanent dis...
Eligibility Criteria
Inclusion
- Minimally 18 years old
- Endo-CABG surgery 5 years ago (group 1)
- PCI surgery 5 years ago (group 2)
- Healthy volunteer 5 years ago (group 3)
Exclusion
- Medical history of
- Stroke or POCD
- Symptomatic carotid disease
- Dementia
- Renal dysfunction (GFR \< 30 ml/min)
- Hepatic dysfunction (Aspartate aminotranspferase (SGOT/AST) or Alanine Amino Transpherase (SGPT/ALT) \> 3x normal limits)
- History of drug, medication or alcohol abuse
- Language barrier or inability to communicate
- Physical abnormality that prevents performing the neurocognitive tests
- Surgical revision or presence of intra-operative major cardiac event (endo-CABG)
- Conversion to cardiac surgery of presence of major cardiac event (PCI)
- Simultaneous valve surgery
- Inability to travel to follow-up moment
Key Trial Info
Start Date :
March 25 2022
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
November 7 2022
Estimated Enrollment :
55 Patients enrolled
Trial Details
Trial ID
NCT05330260
Start Date
March 25 2022
End Date
November 7 2022
Last Update
March 8 2023
Active Locations (1)
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1
Jessa Hospital
Hasselt, Limburg, Belgium, 3500