Status:

COMPLETED

Regent China Post-Market Clinical Follow-up Study

Lead Sponsor:

Abbott Medical Devices

Conditions:

Valvular Heart Disease

Aortic Valve Disease

Eligibility:

All Genders

18+ years

Brief Summary

Regent China Post-Market Clinical Follow-Up (RC-PMCF): this clinical study is to confirm the safety and performance of Abbott's Regent MHV for replacement of native or prosthetic aortic valves in a Ch...

Detailed Description

The purpose of the RC-PMCF study is to meet the post-market clinical followup (PMCF) requirements of the National Medical Products Administration (NMPA). The primary objective of this clinical study i...

Eligibility Criteria

Inclusion

  • Patient is eligible to be implanted with Regent to replace a native or prosthetic aortic valve per Regent's IFU.
  • Subject will be \>18 years of age at time of being consented.
  • Subject, provides written informed consent prior to any clinical investigation-specific procedure.

Exclusion

  • Subject is unable to tolerate anticoagulation therapy.
  • Subject has active endocarditis.
  • Subject is currently participating in another clinical investigation which may interfere with the effectiveness of anticoagulation therapy.
  • Pregnant or nursing subjects and those who plan pregnancy during the clinical investigation follow-up period. Women of child-bearing potential must have a documented negative pregnancy test within one week prior to enrollment.
  • Subject has anomalous anatomy or medical, surgical, psychological or social history or conditions that, in the investigator's opinion, could limit the subject's ability to participate in the clinical investigation or to comply with follow-up requirements of the clinical investigation results.
  • Subject is unable to read or write or has a mental illness or disability that impairs their ability to provide written informed consent.
  • Subject's life expectancy is less than 1 year in the opinion of the Investigator.

Key Trial Info

Start Date :

March 29 2022

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

October 10 2024

Estimated Enrollment :

200 Patients enrolled

Trial Details

Trial ID

NCT05330468

Start Date

March 29 2022

End Date

October 10 2024

Last Update

October 27 2025

Active Locations (5)

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Page 1 of 2 (5 locations)

1

The People's Hospital of Gaozhou

Gaozhou, China

2

The Second Affiliated Hospital of Nanchang University

Nanchang, China

3

Ningbo Medical Center Lihuili Hospital

Ningbo, China

4

Wuhan Union Hospital of China

Wuhan, China