Status:
COMPLETED
Body Weight and Carb Metabolism
Lead Sponsor:
University of Bath
Collaborating Sponsors:
University of Birmingham
Conditions:
Exercise Metabolism
Eligibility:
All Genders
18-60 years
Brief Summary
Whilst theoretically, body size should influence the capacity for intestinal carbohydrate absorption and thus exogenous oxidation rates during exercise, there is currently little empirical evidence to...
Eligibility Criteria
Inclusion
- Able to cycle continuously for 2 hours at a moderate intensity
- VO2max of between 40-75 mL/kg/min
- Fat-mass index (determined by dual energy x-ray absorptiometry) \< 5.5 kg·m-2
Exclusion
- Diagnosed disorders of the gastrointestinal tract (e.g. crohn's, colitis etc.)
- People following a low-carbohydrate, high-fat diet
- Pregnant or lactating
- Diagnosed cardiovascular disease
- Possible symptoms of cardiovascular disease
- Diagnosis of diabetes of any type
- Hypercholesterolaemia (total cholesterol ≥ 6.2 mmol/L
- Hypertension (systolic blood pressure ≥140 mmHg or diastolic blood pressure ≥90 mmHg)
- Current smoker
- Family history of coronary artery disease (first-degree relative \<60 years)
- Prevalence of vascular disease
- Autonomic neuropathy
- Kidney disease
- Diagnosed pulmonary disease (e.g. chronic obstructive pulmonary disease, asthma, interstitial lung disease or cystic fibrosis)
- Blood borne disease or infection
- Osteoporosis
- Osteoarthritis
- Blood clotting disorders
- Food intolerances/allergies (these may not specifically exclude you- please talk to the investigator)
- Sensitivity or allergy to anaesthetic
Key Trial Info
Start Date :
March 1 2022
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
July 27 2024
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT05330481
Start Date
March 1 2022
End Date
July 27 2024
Last Update
September 19 2024
Active Locations (1)
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1
Department for Health, University of Bath
Bath, United Kingdom, BA2 7AY