Status:

RECRUITING

Clinical and Molecular Correlates of Response to First Line Treatment in Lichen Planus

Lead Sponsor:

University of Aberdeen

Conditions:

Lichen Planus, Oral

Lichen Planus of Vulva

Eligibility:

All Genders

18+ years

Brief Summary

Lichen planus is a common inflammatory (swelling and pain of tissue) disease in the general population that affects mostly the mouth although skin and genital areas can also be affected. It can cause ...

Detailed Description

PARTICIPANT SELECTION AND ENROLMENT IDENTIFYING PARTICIPANTS All participants will be selected from attendants of the Oral \& Maxillofacial Unit, Women's Day Clinic and Aberdeen Dental School in the ...

Eligibility Criteria

Inclusion

  • Patients aged more than 18 years, with confirmed histopathological diagnosis of lichen planus and undergoing topical steroid therapy.
  • Participants who have the capacity to consent.
  • Participants who show a willingness to attend an initial appointment and a follow-up post-treatment appointment.

Exclusion

  • Patients on systemic steroids and other immunosuppressive agents for the treatment of lichen planus
  • Cases of graft versus host disease or those suffering from other systemic inflammatory conditions mimicking lichen planus (e.g. connective tissue disease).
  • Pregnant and lactating participants.
  • Inability to consent.

Key Trial Info

Start Date :

February 7 2022

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

September 30 2026

Estimated Enrollment :

110 Patients enrolled

Trial Details

Trial ID

NCT05330572

Start Date

February 7 2022

End Date

September 30 2026

Last Update

April 10 2024

Active Locations (2)

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Page 1 of 1 (2 locations)

1

University of Aberdeen

Aberdeen, Aberdeen, Scotland, United Kingdom, AB24 3FX

2

Aberdeen Dental School

Aberdeen, United Kingdom, AB25 2ZR