Status:

UNKNOWN

Transcranial Pulse Stimulation Open-label Self-controlled Trial For Mild Neurocognitive Disorder

Lead Sponsor:

The University of Hong Kong

Collaborating Sponsors:

Storz Medical AG

Conditions:

Mild Neurocognitive Disorder

Eligibility:

All Genders

60+ years

Phase:

NA

Brief Summary

Background: A significant proportion of older adults suffered from age-related diseases particularly dementia, also known as major neurocognitive disorder (NCD), which is becoming a worldwide health ...

Detailed Description

Background Age-related diseases, particularly dementia, now known as major neurocognitive disorder (NCD), are a great health burden in Hong Kong and worldwide. Interventions that aim to ameliorate cog...

Eligibility Criteria

Inclusion

  • 1\. 60 years of age or above
  • 2\. Chinese ethnicity
  • 3\. Mild neurocognitive disorder (NCD) meeting the 5th Edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) criteria
  • 4\. At least 3 months of stable anti-dementia therapy prior to enrolment (unchanged medication, if receiving)
  • 5\. Written informed consent

Exclusion

  • 1\. A HK-MoCA score below the second percentile according to the subject's age and education level
  • 2\. Alcohol or substance dependence
  • 3\. Concomitant unstable major medical conditions or major neurological conditions such as brain tumour, brain aneurysm
  • 4\. Haemophilia or other blood clotting disorders or thrombosis
  • 5\. Significant communicative impairments
  • 6\. Participants with any metal implant in brain or treated area of the head

Key Trial Info

Start Date :

January 20 2020

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

July 30 2024

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT05331560

Start Date

January 20 2020

End Date

July 30 2024

Last Update

April 15 2022

Active Locations (1)

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1

The Hong Kong Jockey Club Building for Interdisciplinary Research

Hong Kong, Hong Kong