Status:

COMPLETED

Comparison of Endoscopic Band Ligation Plus 24-hour Versus 72-hour Terlipressin Therapy

Lead Sponsor:

Instituto Mexicano del Seguro Social

Conditions:

Esophageal and Gastric Varices

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

In the Western world, liver cirrhosis is a significant issue. Acute variceal bleeding (AVB) is a considerable complication of cirrhosis associated with high mortality. Still, the combination of endosc...

Detailed Description

In the Western world, liver cirrhosis is a significant issue. Acute variceal bleeding (AVB) is a considerable complication of cirrhosis associated with high mortality. Still, the combination of endosc...

Eligibility Criteria

Inclusion

  • Patients of 18 years and older
  • Both genders,
  • Diagnosis of liver cirrhosis with a Child-Pugh score ≤ 11 (class B or C)
  • Acute variceal bleeding were included

Exclusion

  • Patients with contraindications to terlipressin (pregnancy, breastfeeding, or severe cardiopulmonary diseases),
  • Presence of sepsis,
  • Multi-organ failure,
  • The requirement of continuous ionotropic or ventilatory support,
  • Bleeding disorders,
  • Hepatocellular carcinoma or other extrahepatic malignanc.

Key Trial Info

Start Date :

January 1 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 30 2021

Estimated Enrollment :

109 Patients enrolled

Trial Details

Trial ID

NCT05331768

Start Date

January 1 2021

End Date

September 30 2021

Last Update

April 18 2022

Active Locations (1)

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1

Centro Médico Nacional de Occidente

Guadalajara, Jalisco, Mexico, 44329