Status:

RECRUITING

OFS in Premenopausal Node+ Breast Cancer With Low Genomic Risk

Lead Sponsor:

Gangnam Severance Hospital

Collaborating Sponsors:

Seoul National University

Conditions:

Breast Cancer

Estrogen Receptor Positive Tumor

Eligibility:

FEMALE

20-50 years

Phase:

PHASE4

Brief Summary

Among ER+HER2- premenopausal patients with N1 who undergoes primary breast surgery, we will identify the patients with a genomic low risk using the multigene-assay (OncoFREE®). In these, ovarian func...

Detailed Description

* Among ER+HER2- premenopausal patients with N1 who undergoes primary breast surgery, we will identify the patients with a genomic low risk using the multigene-assay (OncoFREE®). * In these, ovarian f...

Eligibility Criteria

Inclusion

  • ER+HER2- breast cancer
  • Premenopausal and age \<=50
  • T1 or T2
  • N1 including micrometastasis
  • Genomic Low Risk by OncoFREE test® (1-20)

Exclusion

  • Postmenopausal women
  • ER-negative breast cancer

Key Trial Info

Start Date :

February 6 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

January 1 2033

Estimated Enrollment :

418 Patients enrolled

Trial Details

Trial ID

NCT05333328

Start Date

February 6 2023

End Date

January 1 2033

Last Update

May 22 2025

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Gangnam Severance Hospital

Seoul, Korea, South Korea, 06229

2

Seoul National University Hospital

Seoul, South Korea