Status:
RECRUITING
Sex-differential Host-microbiome CVD Risk - A Longitudinal Cohort Approach
Lead Sponsor:
Charite University, Berlin, Germany
Collaborating Sponsors:
Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK)
Conditions:
Transgender
Gut Microbiome
Eligibility:
All Genders
18-50 years
Brief Summary
The XCVD study investigates the influence of sex hormones on the composition of the gut microbiome and the possible emergence of cardiovascular risk factors. It will follow 200 healthy transgender ind...
Detailed Description
Conducting this innovative study using established scientific methods such as omics platforms, systems biology, and careful CVD phenotyping will allow, for the first time, extensive data collection on...
Eligibility Criteria
Inclusion
- Age 18-50
- Language requirements: German, English
- Previous gender hormone replacement therapy (HRT).
- Ability to give consent and written consent to participate.
- Health insurance (for clarification of incidental findings)
Exclusion
- Diseases or functional disorders that, in the opinion of the study physician, preclude participation in the study.
- Incapacity or other circumstances that do not allow study participants to fully understand the nature, significance and scope of this study.
Key Trial Info
Start Date :
August 29 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2027
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT05334888
Start Date
August 29 2022
End Date
December 31 2027
Last Update
February 9 2024
Active Locations (1)
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1
Experimental and Clinical Research Center, Clinical Research Unit
Berlin, Germany, 13125