Status:

RECRUITING

Hybrid Micro-macro Electrodes in Patients with Epilepsy

Lead Sponsor:

Pierre Mégevand

Collaborating Sponsors:

Swiss National Science Foundation

Wyss Center for Bio and Neuroengineering

Conditions:

Epilepsy

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The aim of the MicroEPI study is to know whether it is possible to use safely a medical device (a micro-electrode) that allows recording the activity of neurons in the human brain. Patients who suffer...

Detailed Description

Epilepsy is a common disease of the brain that can be severe or even cause death. What we call epilepsy is a tendency to suffer from epileptic seizures, which themselves consist in symptoms (e.g. loss...

Eligibility Criteria

Inclusion

  • Patient 18 years old or older suffering from drug-resistant focal epilepsy.
  • Candidate for epilepsy surgery.
  • Requires evaluation with intracranial stereo-EEG electrodes.
  • Able and willing to provide informed consent.

Exclusion

  • Any acute infection (e.g. fever, throat infection).
  • Skin or scalp infection over the implantation site.
  • Thin or fragile skull bones, which would prevent stereo-EEG electrodes from being anchored safely.
  • Increased risk of infections, either from a medical condition or from immunosuppressant medication.
  • Increased risk of bleeding, either from a medical condition or from antiplatelet or anticoagulant medication.
  • Severe concomitant medical disease (including, but not limited to, cardiovascular, respiratory, renal or hepatic disease).
  • Severe concomitant psychiatric disease or major psychological distress.
  • Women who are pregnant or breastfeeding during the study.
  • Patients who have an implanted stimulation device (e.g. pacemaker, defibrillator, neurostimulator).

Key Trial Info

Start Date :

March 30 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

September 1 2027

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT05335187

Start Date

March 30 2023

End Date

September 1 2027

Last Update

September 23 2024

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Inselspital Bern

Bern, Canton of Bern, Switzerland, 3010

2

Hôpitaux Universitaires de Genève

Geneva, CH, Switzerland, 1205