Status:
RECRUITING
Dronabinol After Arthroscopic Surgery
Lead Sponsor:
Northwestern University
Conditions:
Knee Osteoarthritis
Knee Injuries
Eligibility:
All Genders
18+ years
Phase:
PHASE3
Brief Summary
The purpose of the proposed study is to evaluate the efficacy of dronabinol for postoperative pain after arthroscopic surgery of the knee. The investigators hypothesize that dronabinol will relieve pa...
Eligibility Criteria
Inclusion
- Age 18 years or older
- Patient who will undergo arthroscopic surgery of the knee including, but not limited to,
- Meniscectomy
- Synovectomy
- Chondroplasty
- Loose body removal
Exclusion
- Patients under age 18 years
- Patients who cannot provide consent
- Patients who are pregnant, breast feeding, or are trying to become pregnant during the study period
- Patients with an allergy to any of the study drugs
- Patient who are lactose-intolerant
- Revision surgery
- Open surgery
- Comorbidities preventing surgery
- Patients with a history of mania, depression, or schizophrenia
- Patients taking any of the following drugs or supplements
- Anticholinergic agents
- Benzodiazepines
- Central nervous system depressants
- Droperidol
- Hydroxyzine
- Levomepromazine or methotrimeprazine
- Monoamine oxidase inhibitors
- Ritonavir
- Selective serotonin reuptake inhibitors
- Sympathomimetics
- St. John's Wort
- Current diagnosed alcohol or drug abuse
- Patients who cannot or will not abide by the medication restrictions listed below
- Medication restrictions
- Participants must agree to abstain from using recreational or medical marijuana products or cannabidiol (CBD) in any form during the treatment period
- Participants should not drink alcohol or take other drugs while taking the study drug or hydrocodone/acetaminophen
Key Trial Info
Start Date :
June 28 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2027
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT05335252
Start Date
June 28 2022
End Date
June 1 2027
Last Update
April 29 2025
Active Locations (1)
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1
Northwestern University Feinberg School of Medicine
Chicago, Illinois, United States, 60611