Status:
UNKNOWN
IV Dexmedetomidine in the Duration of Spinal Anesthesia With Hyperbaric Bupivacaine: Double Blind Randomized Trial.
Lead Sponsor:
Hospital Central "Dr. Ignacio Morones Prieto"
Conditions:
Anesthesia
Dexmedetomidine
Eligibility:
All Genders
18-65 years
Phase:
PHASE3
Brief Summary
Introduction: Spinal anesthesia produces sensitive and motor block according to the administered local anesthetic. The total duration of surgical anesthesia depends on the dose, intrinsic properties o...
Detailed Description
Neuraxial blockade is produced by interrupting nervous impulse transmission with the administration of a local anesthetic. When the drug in injected directly into the subarachnoid space, it passes thr...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- Previously accepted and signed informed consent.
- Age between 18 and 65 years
- Male or female
- ASA classified I or II
- Undergoing elective lower limb orthopedic surgery
- Neuraxial anesthesia with 10 mg of spinal bupivacaine (2ml at 0.5%)
- Inert epidural catheter
- Exclusion Criteria
- Basal heart rate lower than 55 beats per minute
- Basal mean arterial pressure (MAP) lower than 65 mmHg
- Non-compensated heart disease
- Sinus bradycardia
- Drug allergy or intolerance
- Contraindication for neuraxial blockade
- Coagulopathy
- Lumbar structural pathology and/or vertebral instrumentation
- Local active infection at punction site
- Thrombocytopenia (lower than 80 K platelets)
- Non-controlled psychiatric disease
- Patients that receive drugs such as NSAIDs, acetaminophen and/or opioids within less than 3 hours prior to the procedure
Exclusion
Key Trial Info
Start Date :
January 31 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 15 2022
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT05335655
Start Date
January 31 2022
End Date
June 15 2022
Last Update
June 13 2022
Active Locations (1)
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1
Hospital Central Dr Ignacio Morones Prieto
San Luis Potosí City, Mexico, 78210