Status:

RECRUITING

Post-Vent, the Sequelae: Personalized Prognostic Modeling for Consequences of Neonatal Intermittent Hypoxemia in Preterm Infants at Pre-School Age

Lead Sponsor:

Ann & Robert H Lurie Children's Hospital of Chicago

Collaborating Sponsors:

University of Virginia

Case Western Reserve University

Conditions:

Premature Birth

Asthma in Children

Eligibility:

All Genders

30-83 years

Brief Summary

Despite improved survival of extremely premature infants in recent decades, neonatal intensive care unit (NICU) graduates are diagnosed with asthma, sleep disordered breathing (SDB) in childhood, and ...

Detailed Description

Asthma, SDB, and NDI are common consequences of preterm birth with significant impact on child and family quality of life and public health. To date, the mechanisms leading to these outcomes remain un...

Eligibility Criteria

Inclusion

  • Enrolled in any Institutional Review Board (IRB) protocol of the Pre-Vent Study that had signed consent, or in any IRB protocol of the Pre-Vent Study that authorized re-contact for future research
  • Born \<29 weeks gestational age
  • Age at enrollment less than 7 years old

Exclusion

  • Subject was withdrawn from the Pre-Vent study after signing Pre-Vent consent form, for any reason
  • Subject had no physiological data recorded as part of Pre-Vent
  • Lack of regulatory approval from local IRB or Department of Children and Family Services (DCFS) to recontact subjects
  • Adopted by non-consenting family
  • Parent refused further contact, prior to approach for Post-Vent
  • Infant enrolled in Pre-Vent at Washington University St Louis, which is not a Post-Vent participating site.

Key Trial Info

Start Date :

November 1 2022

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

June 30 2026

Estimated Enrollment :

500 Patients enrolled

Trial Details

Trial ID

NCT05336890

Start Date

November 1 2022

End Date

June 30 2026

Last Update

December 5 2024

Active Locations (1)

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1

Ann & Robert H. Lurie Children's Hospital of Chicago

Chicago, Illinois, United States, 60611