Status:

RECRUITING

KM3D Multicenter Cancer Consortium: Predicting Patient Response Using 3D Cell Culture Models

Lead Sponsor:

Known Medicine, Inc.

Collaborating Sponsors:

M.D. Anderson Cancer Center

Duke Cancer Institute

Conditions:

Cancer

Predictive Cancer Model

Eligibility:

All Genders

18+ years

Brief Summary

This study will assess the ability of the Known Medicine platform to predict the efficacy of certain cancer drug treatments and to validate that tumor organoid drug sensitivity is representative of pa...

Detailed Description

This is a non-interventional clinical study in which (1) cancer tissue that has been resected, biopsied, or drained due to malignant pleural effusion and that is left remaining after (or is not being ...

Eligibility Criteria

Inclusion

  • A demonstrated primary solid cancer for which it is medically indicated and planned to be surgically resected, biopsied, or drained (via malignant pleural effusion).
  • The ability to ship the tissue sample within 24 hours of removal from the patient.
  • Signed and dated consent to giving tissue as well as allowing for de-identified medical history information regarding administered treatments and treatment outcomes to be shared.
  • over 18 years of age

Exclusion

  • Presence of a condition(s) or diagnosis, either physical or psychological, or physical exam finding that precludes participation in the opinion of the Investigator.

Key Trial Info

Start Date :

January 12 2021

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

January 31 2026

Estimated Enrollment :

2000 Patients enrolled

Trial Details

Trial ID

NCT05338073

Start Date

January 12 2021

End Date

January 31 2026

Last Update

April 24 2023

Active Locations (3)

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Page 1 of 1 (3 locations)

1

Mayo Clinic

Rochester, Minnesota, United States, 55905

2

Duke Cancer Institute

Durham, North Carolina, United States, 27710

3

MD Anderson Cancer Center

Houston, Texas, United States, 77030