Status:
UNKNOWN
Effectiveness of Empirical Antibiotic Use in Mild to Moderate Acute Inflammatory Gallbladder Disease
Lead Sponsor:
Seoul St. Mary's Hospital
Conditions:
Cholecystitis, Acute
Eligibility:
All Genders
19-70 years
Phase:
NA
Brief Summary
This clinical trial is an exploratory clinical trial that evaluates the necessity and effectiveness of empirical antibiotic use in mild and moderate acute inflammatory gallbladder diseases that requir...
Detailed Description
Cholecystectomy is the standard treatment for acute cholecystitis, accompanied by pain and fever due to acute inflammation in cholelithiasis patients. Empirical antibiotics are generally used to treat...
Eligibility Criteria
Inclusion
- among patients with mild acute cholecystitis (grade I by Tokyo guidelines) or moderate acute cholecystitis without evidence of gallbladder perforation(grade II)
- cholecystitis with a thickness of 4 mm or more on gallbladder in preoperative imaging
- Gallbladder with surrounding organs due to gallbladder inflammation
- Patients over 19 years of age, under 70 years of age
Exclusion
- patients with elective gallbladder surgery (chronic cholecystitis)
- gallbladder disease not inflammatory disease (GB cancer, GB polyp)
- pregnant women, patients under 18 years of age, over 70 years of age
- patients with simultaneous surgery due to other organ diseases
- immunosuppressed patients; liver transplant patients, kidney transplant patients, acquired immunodeficiency syndrome patients
- patients with hemorrhagic tendency, or with hematologic diseases
- Patients who underwent percutaneous cholecystectomy (PTGBD)
Key Trial Info
Start Date :
May 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
April 30 2024
Estimated Enrollment :
370 Patients enrolled
Trial Details
Trial ID
NCT05339282
Start Date
May 1 2022
End Date
April 30 2024
Last Update
May 6 2022
Active Locations (1)
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1
Department of HBP Surgery, Seoul St. Mary's hospital
Seoul, Seocho-gu, Banopo-dong, South Korea, 137-701