Status:
RECRUITING
Systematic Light Exposure in Pediatric Brain Tumor Survivors
Lead Sponsor:
Baylor College of Medicine
Collaborating Sponsors:
National Institute of Nursing Research (NINR)
St. Jude Children's Research Hospital
Conditions:
Brain Tumor
Eligibility:
All Genders
10-18 years
Phase:
NA
Brief Summary
Children and adolescents treated for a brain tumor often experience fatigue and cognitive symptoms, such as slowed information processing and inattention. These symptoms may cause difficulty carrying ...
Detailed Description
Participants will be randomized to take part in one of two groups: 1. The Bright Light Group will be exposed to bright light (1,000 lux at eye level) using light glasses (Luminette Version 3) for a m...
Eligibility Criteria
Inclusion
- Diagnosed and treated for a brain tumor at Texas Children's Hospital
- Treated with either surgery only or surgery and proton beam radiation therapy
- Treated for tumors other than high-grade gliomas, brain stem gliomas, or atypical teratoid rhabdoid tumors given associated reduced survival rates
- Currently or previously enrolled in longitudinal studies of neurocognitive outcomes in survivors of pediatric brain tumor (Lisa Kahalley, PI; H-29026, H-35681, H-40804, H-40961, H-49380, H-26785, H-41705
- Ages 10-18 years
- At least 1 year post-diagnosis
- Endorsed mild to moderate symptoms of fatigue on the PROMIS
- Approval from Long-Term Survivorship provider
- Adequate vision for computerized tasks
- English-speaking
- Intelligence Quotient (IQ) above 70
Exclusion
- Diagnosis and/or treatment for secondary malignancy in the past 12 months
- Current or previous (within 12 months) suicidal ideation or severe depression requiring immediate intervention
- Presence of photophobia or other eye diseases, seizures, and/or migraines
- Use of photosensitizing medications
- Current or previous use of light therapy
Key Trial Info
Start Date :
October 14 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 1 2026
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT05340881
Start Date
October 14 2022
End Date
July 1 2026
Last Update
September 18 2025
Active Locations (1)
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1
Texas Children's Hospital
Houston, Texas, United States, 77030