Status:
COMPLETED
Comparison of the Effect of Two Anaesthesia Methods in Preventing Perioperative Myocardial Infarcation in Patients With Cardiac Risk Undergoing Total Knee Arthroplasty
Lead Sponsor:
Alexandria University
Conditions:
Myocardial Ischaemia
Eligibility:
All Genders
65+ years
Phase:
NA
Brief Summary
Comparison of the effect of two anaesthesia methods in preventing perioperative myocardial infarction in patients with cardiac risk undergoing total knee arthroplasty
Detailed Description
we enrolled 50 patients of both sex of American society of Anesthesiologists (ASA) physical status II where the presence and/or risk for coronary artery disease (CAD) as well as planned lower extremit...
Eligibility Criteria
Inclusion
- presence and/or risk for coronary artery disease (CAD) as well as planned lower extremity surgery was considered. Presence of CAD was ascertained by history of myocardial infarction and diagnosis of typical angina or atypical angina with a positive stress test \& ECG finding. Risk for CAD included age (\> 65 years old), hypertension, smoking habit, blood cholesterol (\>240 mg/dL), and diabetes.
Exclusion
- 1\) severe impairment of left ventricular function (ejection fraction \< 40 %). 2) renal failure requiring hemodialysis. 3) known allergies to the drugs used in the present study. 4) contraindications to regional blocks (localized infection, and use of an antiplatelet drug within 3 days before the surgery). 5) unusual blood coagulation tests.
Key Trial Info
Start Date :
September 5 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 15 2022
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT05340946
Start Date
September 5 2021
End Date
April 15 2022
Last Update
April 22 2022
Active Locations (1)
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1
Alexandria University Faculty of Medicin
Alexandria, Egypt, 21615