Status:
UNKNOWN
Relationship Between Perioperative Related Factors and Inflammatory Markers and Postoperative Delirium in Elderly Patients With Non-cardiac Major Surgery
Lead Sponsor:
Beijing Friendship Hospital
Conditions:
Preoperative Sleep Disorder
Preoperative Anxiety
Eligibility:
All Genders
60-100 years
Brief Summary
Perioperative neurocognitive impairment, including postoperative delirium (POD), is common in older patients after anesthesia and surgery and is associated with poorer short- and long-term outcomes, i...
Eligibility Criteria
Inclusion
- ①patients over 60 years old;
- ASA grade II-IV;
- major surgery for \>2 hours,
- hospital stay \>2 days.
Exclusion
- ①History of neurological, cerebral or psychiatric diseases;
- History of alcoholism or drug dependence;
- Preoperative delirium, or previous postoperative delirium; ④No obvious visual, auditory, and communication impairment;
- No obvious liver and kidney Functional impairment; ⑥ The surgical site interferes with BIS electrode placement;
- Planned wake-up test during the surgery; ⑧ No follow-up is expected after 1 year.
Key Trial Info
Start Date :
November 1 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2024
Estimated Enrollment :
400 Patients enrolled
Trial Details
Trial ID
NCT05341531
Start Date
November 1 2022
End Date
December 31 2024
Last Update
April 22 2022
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