Status:

COMPLETED

Oral Nutritional Supplementation With HMB Enhance Muscle Quality in Sarcopenic Surgical Patients

Lead Sponsor:

Sengkang General Hospital

Collaborating Sponsors:

Abbott

Conditions:

Sarcopenia

Frailty

Eligibility:

All Genders

40-90 years

Phase:

NA

Brief Summary

Aims: Clinical frailty severely impacts the physical, functional and physiological reserves necessary for the recovery after surgery. Sarcopenia, a multifactorial, multi-organ process which lead to l...

Eligibility Criteria

Inclusion

  • between 40-90 years old
  • are sarcopenia (defined by the Asian Workgroup of Sarcopenia 2019 definition)
  • due to undergo elective major gastrointestinal surgery
  • able to satisfy at least 2 weeks of prehabilitation before surgery
  • ambulant
  • able to comply with physiotherapy and dietician advice

Exclusion

  • Are pregnant
  • Are prisoners
  • Intellectually, mentally or emotionally deemed not able to provide an informed consent and/or are unable to fill up the post-procedure questionnaires
  • Have disease conditions requiring emergent/semi-emergent operation
  • Diabetes on oral hyperglycemic agents (OHGA)
  • Chronic Kidney Disease (CKD) or End-stage Renal Failure (ESRF)
  • Unable to or decline assessment for sarcopenia

Key Trial Info

Start Date :

June 1 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 30 2024

Estimated Enrollment :

47 Patients enrolled

Trial Details

Trial ID

NCT05344313

Start Date

June 1 2022

End Date

June 30 2024

Last Update

October 23 2024

Active Locations (1)

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Sengkang General Hospital

Singapore, Singapore, 544886