Status:

COMPLETED

Evaluation of the Effectiveness of Secukinumab in Patients With Moderate to Severe Plaque Psoriasis

Lead Sponsor:

Novartis Pharmaceuticals

Conditions:

Plaque Psoriasis

Eligibility:

All Genders

18-80 years

Brief Summary

This study was a real-life study which was based on secondary data collection from the electronic or paper medical records from the Dermatology Clinics of the 14 University, Training \& Research Hospi...

Detailed Description

The study was a retrospective, multicenter, cohort study which was based on data collection at week 4,16 and 52 of secukinumab treatment of moderate to severe plaque psoriasis. The observational desi...

Eligibility Criteria

Inclusion

  • A diagnosis of psoriasis
  • Age ≥ 18 years at registry baseline.
  • Patients with a firm diagnosis of chronic plaque psoriasis for at least 6 months before enrollment
  • Secukinumab treatment should be initiated 52 weeks before data collection date
  • Moderate to severe plaque psoriasis with PASI score of ≥10 before initiating secukinumab.

Exclusion

  • Patients diagnosed with others types of psoriasis (pustular psoriasis, erythrodermic psoriasis etc) are excluded.
  • Previous exposure to secukinumab or any other biologic drug directly targeting IL-17A or IL-17RA

Key Trial Info

Start Date :

July 9 2020

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

August 31 2021

Estimated Enrollment :

277 Patients enrolled

Trial Details

Trial ID

NCT05344482

Start Date

July 9 2020

End Date

August 31 2021

Last Update

July 1 2022

Active Locations (1)

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1

Novartis Investigative Site

East Hanover, New Jersey, United States, 07936-1080