Status:

COMPLETED

The Correlation Between CITED2 and Collateral Circulation in Acute Ischemic Stroke

Lead Sponsor:

Zhujiang Hospital

Conditions:

Acute Ischemic Stroke

Eligibility:

All Genders

18-80 years

Brief Summary

Evaluating the collateral circulation of acute ischemic stroke (AIS) mainly depends on the imaging examination. At present, there is no effective and sensitive biomarker for collateral circulation. Th...

Eligibility Criteria

Inclusion

  • the first-time onset or previous stroke with mRS score ≤1, and the onset time less than 3 days without intravenous thrombolysis or endovascular therapy ;
  • age range of 18 to 80 years old;
  • patients with a clinical diagnosis of acute ischemic stroke; ④ NIHSS score ≥4; ⑤ patients volunteer to participate in this study and signed a written informed consent

Exclusion

  • ①the patients with AIS combined with other diseases that may affect the CITED2 and VEGF expression, such as acute myocardial infarction, peripheral artery occlusion disease and congenital heart defect;
  • the patients exhibited serious heart, live or kidney diseases; ③disturbance of consciousness or mental illness; ④ patients with tumor; ⑤ pregnant and lactating patients.

Key Trial Info

Start Date :

November 1 2020

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

March 1 2024

Estimated Enrollment :

130 Patients enrolled

Trial Details

Trial ID

NCT05345366

Start Date

November 1 2020

End Date

March 1 2024

Last Update

June 6 2024

Active Locations (1)

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Zhujiang Hospital

Guangzhou, Guangdong, China, 510260