Status:
RECRUITING
Endovascular Denervation for the Treatment of Patients With Peripheral Arterial Disease
Lead Sponsor:
Zhongda Hospital
Conditions:
PAD
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
Sympathetic overactivity partly promotes the development of peripheral artery disease which mainly leads to ischemia of the lower limbs. Endovascular arterial denervation (ED) is a minimally invasive ...
Detailed Description
Peripheral arterial disease(PAD) show insufficient blood supply of diseased limbs, which causes intermittent claudication of lower limbs, reduced skin temperature, pain, and chronic progressive diseas...
Eligibility Criteria
Inclusion
- eligible subjects aged 18-75 years,
- clinically confirmed PAD patients in Rutherford category II-VI.
Exclusion
- thrombolytic therapy performed within 30 days,
- patients who had undergone vascular bypass surgery before this study,
- allergy or contraindication of antiplatelet drugs, anticoagulants, thrombolytic drugs and contrast agents,
- patients with obvious bleeding tendency, coagulation dysfunction, hypercoagulability and blood system diseases,
- serious liver and kidney diseases,
- history of hemorrhagic stroke within the last 1 month or ischemic stroke or transient ischemic attack within 2 weeks,
- pacemaker implants,
- patients who are pregnant, breast-feeding or planning pregnancy,
- expected survival \< 24 months.
Key Trial Info
Start Date :
April 25 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 30 2026
Estimated Enrollment :
54 Patients enrolled
Trial Details
Trial ID
NCT05345431
Start Date
April 25 2022
End Date
June 30 2026
Last Update
April 25 2022
Active Locations (1)
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1
Zhongda Hospital, Southeast University
Nanjing, Jiangsu, China