Status:
RECRUITING
Efficacy and Safety of Aspirin in Patients With Chronic Coronary Syndromes Without Revascularization
Lead Sponsor:
Takeshi Morimoto
Conditions:
Stable Angina Pectoris
Coronary Artery Disease
Eligibility:
All Genders
20+ years
Phase:
PHASE4
Brief Summary
The purpose of this study is to evaluate the efficacy and safety aspirin in patients with chronic coronary syndromes without revascularization.
Detailed Description
Aspirin for secondary prevention in the acute phase of acute coronary syndromes has been established. Although it is still disputable about the duration, there is also a consensus for antiplatelet the...
Eligibility Criteria
Inclusion
- Patients with chronic coronary syndromes with ≧50% diameter stenosis in one or more major coronary vessels/major branches on coronary CT or coronary angiography but not eligible for coronary revascularization
- Patients for whom consent can be obtained
Exclusion
- Patients with history of acute coronary syndromes (ACS)
- Patients with history of percutaneous coronary intervention (PCI) or coronary artery bypass graft (CABG)
- Patients with left main trunk stenosis (≥50%)
- Patients for whom aspirin administration is mandatory
- Patients undergoing antithrombotic therapy other than aspirin
- Patients with atrial fibrillation
- Patients with history of stroke within six months
- Patients scheduled for major surgical procedures that will require aspirin discontinuation
- Patients with contraindication of aspirin
- Patients expected to have a prognosis of 1 year or less due to comorbidities
- Women of child-bearing potential or women who have a positive pregnancy test at enrolment or randomization
- Patients who are judged by attending physicians to be inappropriate to participate in this study
Key Trial Info
Start Date :
June 14 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2030
Estimated Enrollment :
2890 Patients enrolled
Trial Details
Trial ID
NCT05347069
Start Date
June 14 2022
End Date
December 1 2030
Last Update
March 11 2025
Active Locations (1)
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1
Kyoto University Hospital
Kyoto, Japan