Status:
RECRUITING
Comparing Direct vs Indirect Methods for Cascade Screening
Lead Sponsor:
University of Maryland, Baltimore
Conditions:
Long QT Syndrome
Familial Hypercholesterolemia
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
An important aspect of successful genomic medicine implementation is developing effective approaches for screening at-risk family members after probands are identified, also known as cascade screening...
Detailed Description
Individuals who are known to carry the KCNQ1 Met224Thr or APOB Arg3527Gln variant will be eligible to participate. After providing consent and being deemed eligible, individuals will be randomized in ...
Eligibility Criteria
Inclusion
- Proband
- KCNQ1 Thr224Met or APOB R3527Q carrier
- 18 years or older
- Proband
Exclusion
- None
- Family Inclusion Criteria:
- 1st degree relative of a KCNQ1 Thr224Met or APOB Arg3527Gln carrier
- Family
Key Trial Info
Start Date :
May 15 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 1 2027
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT05348564
Start Date
May 15 2023
End Date
March 1 2027
Last Update
April 18 2025
Active Locations (1)
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1
University of Maryland Amish Research Clinic
Lancaster, Pennsylvania, United States, 17602