Status:

TERMINATED

A Study to Evaluate RIST4721 in Hidradenitis Suppurativa (HS)

Lead Sponsor:

Aristea Therapeutics, Inc.

Conditions:

Hidradenitis Suppurativa

Eligibility:

All Genders

18+ years

Phase:

PHASE2

Brief Summary

A Randomized, Double-blinded, Placebo-controlled, Phase 2a Study to Evaluate the Efficacy and Safety of RIST4721 in Subjects with Hidradenitis Suppurativa

Eligibility Criteria

Inclusion

  • Diagnosis of HS for at least 1 year prior to screening
  • HS lesions must be present in at least 2 distinct anatomic areas
  • A total AN count (sum of abscesses and inflammatory nodules) \> 6 across all anatomical sites at both the screening and baseline visits
  • Willing to use contraception for the duration of the study

Exclusion

  • Presence of other skin conditions which may interfere with study assessments
  • Presence of active, chronic or latent bacterial, viral, fungal mycobacterial infection (including latent TB) or history of infection within 4 weeks of screening
  • Body Mass Index (BMI) \>48kg/m2
  • Breastfeeding or pregnant

Key Trial Info

Start Date :

July 18 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 28 2023

Estimated Enrollment :

25 Patients enrolled

Trial Details

Trial ID

NCT05348681

Start Date

July 18 2022

End Date

February 28 2023

Last Update

June 13 2023

Active Locations (12)

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Page 1 of 3 (12 locations)

1

Cahaba Dermatology & Skin Center

Birmingham, Alabama, United States, 35244

2

Investigate MD, LLC

Scottsdale, Arizona, United States, 85255

3

USC IDS Pharmacy

Los Angeles, California, United States, 90033

4

Florida Academic Centers Research and Education, LLC

Coral Gables, Florida, United States, 33134